"目录号: HY-14471

Others-

Cetilistat是胰腺癌和胃肠道脂酶的抑制剂。它有糖尿病和非糖尿病的肥胖治疗中有很大的作用。

Others

相关产品

SBE-β-CD-MPTP hydrochloride-Cyclosporin A-Etomoxir-Auranofin-GKT137831-Ceruletide-Acetylcysteine-JC-1-BPTES-Brassinolide-FCCP-IPTG-MTT-RSL3 1S,3R--

生物活性

Description

Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.

Clinical Trial

NCT00148382

Alizyme

Obesity

April 2005

Phase 1

NCT00156897

Alizyme

Non-Insulin-Dependent Diabetes Mellitus-Obesity

December 2004

Phase 2

NCT00148382

Alizyme

Obesity

April 2005

Phase 1

NCT00156897

Alizyme

Non-Insulin-Dependent Diabetes Mellitus-Obesity

December 2004

Phase 2

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References

[1].Andrew Bryson, Stephan de la Motte,et al. Reduction of dietary fat absorption by the novel gastrointestinal lipase inhibitor cetilistat in healthy volunteers.Br J Clin Pharmacol. 2009 Mar; 67(3): 309–315.

[2].Melvin George, Muthukumar Rajaram,et al. New and Emerging Drug Molecules Against Obesity.J CARDIOVASC PHARMACOL THER January 2014 vol. 19 no. 1 65-76

[3].Rebeca Carter, Angelina Mouralidarane,et al. Recent advancements in drug treatment of obesity.Clin Med October 1, 2012 vol. 12 no. 5 456-460