临床应用视角看DL算法(2018-11-16)

Radiology

1. Deep Learning for Triage of Chest Radiographs: Should Every Institution Train Its Own System? (paper

文章贡献:用三个well-known网络:AlexNet, ResNet-18和DenseNet-121对200000张胸部X光进行分类,用ImageNet预训练的权重。DenseNet-121性能最好(AUC=0.96),AlexNet最差,但是不同网络之间的差距很小。经典的机器学习算法SVM也做了比较,效果也还不错(AUC=0.93),但是substantially inferior to CNN.

How could one use such a system? 作者建议:It could be used for triage in areas without access to trained radiologists and for workflow prioritization in clinics with staff shortages.

算法+人的组合性能最好:Alternatively, the output of the network can be averaged with a rating provided by a human reader. Dunnmon et al showed that such a combined human and artificial intelligence system achieves an AUC of 0.98, which is significantly better than the computer system alone, and achieves a higher accuracy than human reading alone (the best network alone still has slightly lower accuracy than human reading).

训练数据对网络性能的影响: 超过2W后性能没显著提升。Experimental results with training sets of 2000, 20 000, and 200 000 images are compared. Results when using only 2000 images are substantially worse, but the difference between 20 000 and 200 000 training images is insignifcant, as measured in a hold-out test set of 1000 images that were carefully reannotated by expert readers. 就该任务而言,单个机构搜集2W左右的数据就能训练一个高性能的网络,收集这么多数据对大多数机构都是可行的。

这是引人深思的观点(thought-provoking statement)。这违背了(run counter)了本期刊的notion以及 the regulatory authorities。通常我们要求算法必须在大的多中心的数据集上验证。

编辑的期望:不仅仅给出二值的预测结果,还要检测出图像中有不正常的区域。It would be advisable to train systems not only to provide a binary output label but also to detect specifc regions in the images with specifc abnormalities. This would require annotation of such regions on many training images. Tis would be a step toward a deep-learning network that explains to the user why it arrived at the overall conclusion that examination results might be abnormal.

2. Methodologic Guide for Evaluating Clinical Performance and Effect of Artificial Intelligence Technology for Medical Diagnosis and Prediction (paper

最后编辑于
©著作权归作者所有,转载或内容合作请联系作者
平台声明:文章内容(如有图片或视频亦包括在内)由作者上传并发布,文章内容仅代表作者本人观点,简书系信息发布平台,仅提供信息存储服务。

推荐阅读更多精彩内容

  • rljs by sennchi Timeline of History Part One The Cognitiv...
    sennchi阅读 7,499评论 0 10
  • 昨天就大肆渲染了今天欲来的台风天气,广州的幼儿园与中小学纷纷发布停课停工通知,朋友圈立即沸腾起来。少数工作者欢喜,...
    归缓缓阅读 164评论 0 0
  • 住房的楼下不知是谁养了一只猫,这两日好几次听到猫的叫声,“喵喵喵”地一声强一声弱地叫唤着,那尖细而略显单薄的声音中...
    燃燃的小书屋阅读 332评论 0 8
  • 阿迪又一次陷入了情绪低潮期,“你们都那么厉害,我有时候真的挺没信心的”。 短短几分钟的对话,她多次提到“我不行”、...
    筝小钱阅读 794评论 0 49
  • 《遇见》遇见是一种自然,遇见是一种缘分,遇见也是一种注定。
    cb9fa4682249阅读 239评论 0 0