openpyxl
The recommended package for reading and writing Excel 2010 files (ie: .xlsx)
xlsxwriter
An alternative package for writing data, formatting information and, in particular, charts in the Excel 2010 format (ie: .xlsx)
xlrd
This package is for reading data and formatting information from older Excel files (ie: .xls)
xlwt
This package is for writing data and formatting information to older Excel files (ie: .xls)
xlutils
This package collects utilities that require both xlrd and xlwt, including the ability to copy and modify or filter existing excel files.
NB: In general, these use cases are now covered by openpyxl!
总结来说用openpyxl没错的
