Introduction
NCBI
National Center for Biotechnology Information 美国国家生物技术信息中心
Database | Intro |
---|---|
GenBank | DNA sequences |
PubMed | biomedical literature |
Epigenomics | Other |
The NCBI houses a series of databases relevant to biotechnology and biomedicine and an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for the biomedical literature. Other databases include the NCBI Epigenomics database. All these databases are available online through the Entrez search engine.
Blast
BLAST finds regions of similarity between biological sequences.
寻找生物序列之间的相似性
The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance.
Quick Start
NCBI Home
NCBI - BLAST
https://blast.ncbi.nlm.nih.gov/Blast.cgi
Tools | Function |
---|---|
Nucleotide BLAST | 根据DNA检索DNA相似序列 |
blastx | 根据DNA检索转录出来的蛋白质序列 |
tblastn | 根据蛋白质序列检索对应的DNA序列 |
Protein BLAST | 根据蛋白质序列检索蛋白质序列 |
这里我们根据DNA序列来检索, 所以选择Nucleotide BLAST
物种 人类
待搜索的DNA序列
TAGTGAGTTATCGAACTTGAGGGCAT
获取结果