Speak：后一般加语言名称，是动词，如He can speak Chinese.
call：一般用于打电话中或给人取名字、介绍别人的名字，如：He will call me later.
tell:告诉，如：He is talling me an interesting story.
1. tell 意为“告诉、讲述”，指某人把某事、信息传送给别人或讲述一件事。如：
He tells me that he wants to be a teacher. 他告诉我说他想成为一位教师。
Father always tells interesting stories to us. 爸爸总是给我们讲有趣的故事。
tell sb sth 意为“告知某人某事”。如：
He told me something about his past. 他告诉我一些他的往事。
tell sb to do sth 意为“告诉某人去做某事”。如：
David told his son to do the homework. 大卫要他的儿子去做作业。
2. speak 意为“说话、讲话”，后面主要接语言。如：
He can speak English and a little Chinese. 他能讲英语和一点汉语。
speak to 意为“和.....讲话、谈话”。如：
Can I speak to Mr Zhang? 我能和张先生讲话吗？
speak of 意为“提到、说起”。如：
The book speaks of my hometown. 那本书提到我的家乡。
3. talk 意为“谈话、讲话”，如果只有一方对另一方说话时，一般用 talk to；如果双方或多方交谈，多用 with。如：
Please talk to him right now. 请立即同他谈话。
He is talking with his friend. 他在和朋友交谈。
talk about 意为“谈论......”。如：
They are talking about the movie. 他们在谈论那部电影。
have a talk with 意为“与......交谈”。如：
Can I have a talk with you? 我可以和你交谈吗？
4. say 意为“说”。如：
Can you say it in English once more? 你能用英语再说一遍吗？
say to 意为“对......说”。如：
He said to his students they would have a test. 他对他的学生说他们将进行一次测验。
