We should stop doing the same things that we have been  doing that haven't been working.

stop doing sth 停下正在做的事

stop to sth 停下来去做某事

Every father and mother dwelt in fear and trembling lest their daughter should be selected as  the next victim.

dwelt in 陷入

trembling 焦虑，担心

lest 以免，唯恐

They end up getting defensive instead of going on the offensive.

instead of 替代，而不是

end up (doing)最终成为，以...结尾

They feel as if the dream the generations fought for is slowly slipping away.

fight for 争取

slip away 渐行渐远

I think so much is at stake right now, that running for president can't be about just ambition this time, there is got to be a rationale.

at stake 紧要关头

ambition 野心，抱负

rationale理论基础，逻辑

That, i think, is what's going to be necessary to lead us out of the problems that we're in right now.

And the damage that has been done over the last seven years in our standing in the world is so significant that we have to have the next president engage in a level of personal presidential diplomacy that i think is unmatched at least since world war Ⅱ.

significant 重要的，值得注意的

engage 从事