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sparse稀少的，Data were drawn from 2 cohorts of subjects数据来自两组受试者， undergoing screening colonoscopy进行结肠镜检查，advanced neoplasm晚期肿瘤，Performance of risk models风险模型的性能，More than 1.8 million people were newly diagnosed with CRC, and approximately 881,000 deaths were due to CRC in 2018  2018年，新诊断出180多万人患有CRC，约88.1万人死于CRC。The natural history of CRC usually involves slow progression from precancerous polyps to cancer, which offers opportunities for screening and early detection。结直肠癌的自然史通常包括从癌前息肉到癌症的缓慢进展，这为筛查和早期发现提供了机会，Of note值得注意的是，establishes证实，

outpatient department of门诊部  To identify ，为了什么  we performed LEfSe analysis on the faecal microbiota composition of the 91 steroidnaïve individuals with AIH and 98 healthy controls 我们对91例AIH类固醇依赖者和98例健康对照组的粪便微生物群进行了LEfSe分析，Most noticeably，最明显的是，demonstrated the strongest correlation with the disease status，显示出与疾病状态的最密切关系 Again, Veillonella was the genus most significantly associated with disease status 同样，细脉线虫是与疾病状态最显著相关的属（p=0.0014）。Intriguingly有趣的是，underscoring强调 After controlling for the confounders with MaAsLin 用MaAsLin控制混杂因子后，whereas 而 ，depleted大量减少，

There is growing evidence that越来越多的证据表明， Herein，在本文中，delineated 描述，relative abundances 相对丰度，The most notable finding was that最值得注意的发现是，Remarkably值得注意的是，which is in agreement with our finding that，这与我们的发现一致，Taken together综上所述，it is plausible that它可合理的能是，It is worth noting that值得注意的是