肺细胞类型markers

Feature plots of signature genes used to identify mouse lung cell populations

The following genes were used to identify general populations of cells:

  • immune cells (Ptprc),
  • epithelial cells (Epcam),
  • endothelial cells (Pecam1, Lyve1, Vwf)
  • mesenchymal cells (Col1a2).

The following genes were used to identify specific cell populations within the main types of cells:

  • T cells (Cd3e),
  • B cells (Cd19),
  • myeloid cells (Fcgr1),
  • neutrophils (Mmp9),
  • type I pneumocytes (Akap5),
  • type II pneumocytes (Sftpc),
  • ciliated epithelial cells (Foxj1),
  • club cells (Scgb1a1),
  • lymphatic endothelial cells (Pecam1, Thy1),
  • fibroblasts (Pdg fra)
  • pericytes and smooth muscle cells (Acta2)
  • mesothelial cells (Msln)
  • platelets (Pf4)
Nature, 28 Oct 2020, 587(7834):466-471
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