trouble   to cause inconvenience or discomfort to

麻烦,让某人感到痛苦或焦虑

worry，concern

例：

He was troubled by his health.

Many students today are constantly troubled by their inability to concentrate.

People are increasingly troubled by overload of information so much so that they end up buying many online mini-courses that they do not actually need.

Many international cities, say Los Angeles, Beijing, and New Delhi, are troubled by traffic congestion.

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作业

1）翻译：最困扰很多二线城市的是人才的短缺。

It is talent shortage that troubles many second-tier cities most. 

2）场景：让我焦虑的不是厄运是否来到，而是何时来到。

What throubles me is not a matter of if but when the misfortune comes.