"目录号: HY-14657
Membrane Transporter/Ion Channel-
Dantrolene钠盐是一种钙通道蛋白抑制剂, 抑制钙离子从肌浆释放, Dantrolene钠盐水合物是一种骨骼肌松弛药。
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生物活性
Description
Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
Clinical Trial
University of Massachusetts, Worcester-American Heart Association
Subarachnoid Hemorrhage-Cerebral Vasospasm
October 2009
Phase 1-Phase 2
Medical University of Vienna
Hyperthermia
May 2008
Phase 2-Phase 3
University of Massachusetts, Worcester-Massachusetts General Hospital
Cerebral Vasospasm After Subarachnoid Hemorrhage
July 2007
Phase 1-Phase 2
Eagle Pharmaceuticals, Inc.-Quintiles, Inc.
Heat Stroke
September 2015
Phase 2
Eagle Pharmaceuticals, Inc.
Drug Toxicity Psychotropic Agents Psychostimulants
July 2017
Phase 2
Washington University School of Medicine
Wolfram Syndrome-Diabetes Mellitus-Optic Nerve Atrophy-Ataxia
January 2017
Phase 1-Phase 2
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