多肽介绍
多肽是氨基酸以肽键连接在一起形成的化合物，具有多种生物学功能，例如抗血栓形成、抗高血压、抗菌、抗病毒、抗癌、抗氧化、免疫调节、降胆固醇等，目前已广泛用于功能分析、抗体研究、疫苗开发及药物研发等领域。
MCE 配备强大的技术人才团队和国际先进的设备，提供全方位的高质量定制肽服务，包括快速肽合成、标准化学肽合成、肽修饰、肽库和重组多肽表达，以满足生物与药物发现研究中不断增长的多肽需求。
■可选规格： 毫克（mg）级至公斤（kg）级。
■纯度范围： 粗肽、脱盐、70% 至 98%。
■广泛修饰： 可提供酰胺化、乙酰化、甲基化、磷酸化、标记及偶联等 300+ 种不同 修饰。
■合成技术： 结合固相合成及液相合成，微波和连接技术。
■免费咨询： 专业的 MCE 技术团队为您解答多肽定制的售前与售后的技术问题。
■N 端修饰
•Ac
•Allyl
•Cholesteryl-
•N-Propargylglycine-
•Fmoc
•Acryl
•Fructose-
•A
•CBZ
•Alloc
•Glucose-
•BPS-
•Boc
•Pyr
•Morpholine-4-carbonyl-
•Bz
•D-Pyr
•NTriAc
•Trans-Cinnamoyl
•Bz (5-NH2,2-NO2)
•LA-
•PhAc
•2-Furoyl
•Bz (4-F)
•Mpa-
•Py-Ac
•Methacryl-
•Bz (4-NO2)
•Tos
•N-Amidinoglycine
•BPA-
■C 端修饰
•-pNA
•-OMe
•-ONP
•-OSu
•-NH2
•-OEt
•-AMC
•-NHMe
•-ol
•-OBzl
•-AFC
•-NHEt
■脂肪酸化
•For
•MeOSuc
•5-Hexynoic acid
•F-Lau-
•MeOCO
•Iba
•Heptanedioic acid
•Myr-
•2-Br-Ac
•pentenoic acid
•Oct-
•F-Myr-
•2-Cl-Ac
•pentinoyl
•F-Oct-
•Pentadeconyl-
•2-I-Ac
•Hex-
•Dec-
•Pal-
•OH-Ac
•5-heptenoic acid
•Sebacic acid
•Cys (Pal)
•3-Bromopropionyl
•Trans-3-hexenoyl-
•F-Dec-
•Pam3C-
•But-
•Linoletic-
•Undecyl-
•Ste-
•Suc
•10,12-Pentacosadiynoic acid
•Lau-
•Octanedioic acid
■甲基化
•Lys (Me)
•Arg (Me)
•Tyr (Me)
•Tyr (Et)
•Lys (Me2)
•Arg (Me2)asymmetrical
•Thr (Me)
•D-Tyr (Et)
•Lys (Me3)
•Arg (Me2) symmetrical
•Ser (Me)
■磷酸化
•pSer
•D-pSer
•Di-sites in sequence
•4-sites in sequence
•pTyr
•D-pTyr
•Tri-sites in sequence
•5-sites in sequence
•pThr
•D-pThr
■支肽
•Symmetric 2 Branches
•Symmetric 4 Branches
•Symmetric 8 Branches
•Lys symmetric 2 Branches
•Lys symmetric 4 Branches
•Lys symmetric 8 Branches
•Orn symmetric 2 Branches
•Orn symmetric 4 Branches
•Orn symmetric 8 Branches
•Glu 2 Branches (Pure)
•Glycerol 3 Branches ester
•Thr (Peptide2)
•Ser (Peptide2)
•Lys (Peptide2)
■环肽
•Mono Disulfide bridge
•Double Disulfide bridge
•Triple Disulfide bridge
•Random Triple Disulfide bridge
•Same Sequence Inter-Disulfide bridge by Cys oxidation
•Different Sequence Inter-Disulfide bridge by Cys oxidation
•Oxidation between Se-Cys
•Amide Cyclic (end)
•Amide Cyclic (side chain) by Lys
•Amide Cyclic (side chain) by Orn
■荧光/染料标记
•Biotin-
•FITC-
•Dansyl-
•Lys (Dnp)
•DeThioBiotin
•-ED-FITC
•-EDDansyl
•D-Lys (Dnp)
•-EDBiotin
•-Lys (FITC)-
•-Lys (Dansyl)-
•Dab (Dnp)
•Glu (Biotin-PEG2)
•-Lys (FITC)
•-Lys (Dansyl)
•Dap (Dnp)
•-Lys (Biotin)-
•Lys (Ahx-FITC)
•Dansli-e-Lys
•-EDDnp
•-Lys (Biotin)
•FITC-e-Lys
•Dansyl-Ahx-
•-Lys (LC-Biotin)-
•FITC-Ahx-
•5-FAM-
•-Lys (LC-Biotin)
•5-TAMRA-
•5,6-FAM
•Biotin-e-Lys
•5 (6)-TAMTA-
•6’FAM
•Lys (S-S-Biotin)
•-EDYAMRA
•-ED-5-FAM
•Biotin-Ahx-
•-Lys (TAMRA)-
•-Lys (5-FAM)-
•Orn (Bio)
•-Lys (5-TAMRA)
•Lys (5,6-FAM)
•MCA-
•5-TAMRA-e-Lys
•-Lys (5-FAM)
•-Lys (MCA)-
•5-TAMRA-Acp
•5-FAM-E-Lys
•-Lys (MCA)
•5-FAM-Ahx-
•Lys (MCA)-
■BSA、KLH、OVA 偶联
•BSA-Peptide N terminus
•KLH-Peptide N terminus
•OVA-Peptide N terminus
•BSA-Peptide C terminus
•KLH-Peptide C terminus
•OVA-Peptide C terminus
•BSA-Peptide via Cys
•KLH-Peptide via Cys
•OVA-Peptide via Cys
■Phe & Tyr 衍生物
•D-2-Cl-Phe
•D-4-F-Phe
•L-2-Me-Phe
•L-3-I-Tyr
•L-2-Cl-Phe
•L-4-F-Phe
•D-4-Me-Phe
•D-3,5-DiI-Tyr
•D-3-Cl-Phe
•D-4-NO2-Phe
•L-4-Me-Phe
•L-3,5-DiI-Tyr
•L-3-Cl-Phe
•L-4-NO2-Phe
•D-4-NH2-Phe
•D-3-NO2-Tyr
•D-4-Cl-Phe
•D-4-I-Phe
•L-4-NH2-Phe
•L-3-NO2-Tyr
•L-4-Cl-Phe
•L-4-I-Phe
•D-3-Cl-Tyr
•D-3,5-DiNO2-Tyr
•D-3,4-DiCl-Phe
•D-3-CN-Phe
•L-3-Cl-Tyr
•L-3,5-DiNO2-Tyr
•L-3,4-DiCl-Phe
•L-3-CN-Phe
•D-3,5-DiCl-Tyr
•L-3-F-Tyr
•D-4-Br-Phe
•D-4-CN-Phe
•L-3,5-DiCl-Tyr
•L-4-NO2-Phg
•L-4-Br-Phe
•L-4-CN-Phe
•D-3,5-DiBr-Tyr
•D-4-NO2-Phg
•D-3-F-Phe
•D-2-Me-Phe
•L-3,5-DiBr-Tyr
•L-3,5-DiF-Phe
•L-3-F-Phe
•D-3-I-Tyr
■Linker
•Gly
•Ava
•AEA
•GABA
•Beta-Ala
•Ahx
•Ado
•Mini-PEG
•Mini-PEG2
•Mini-PEG3
•PEG4
■树脂
•peptide on Wang Resin
•peptide on 2-CTC Resin
•peptide on Rink Amide AM Resin
•peptide on Rink Amide MBHA Resin
■D 型氨基酸
•D-Ala
•D-Lys
•D-Glu
•D-Tyr
•D-Arg
•D-Met
•D-Gln
•D-Thr
•D-Asp
•D-Pro
•D-His
•D-Trp
•D-Asn
•D-Phe
•D-Leu
•D-Val
•D-Cys
•D-Ser
■同型氨基酸
•Har
•HomoCit
•beta-HomoMet
•beta-HomoSer
•D-Har
•D-HomoCit
•beta-HomoPro
•beta-HomoThr
•Hcy
•HomoLeu
•beta-HomoVal
•beta-HomoTrp
•HPh
•HomoPro
•beta-HomoAsp
•beta-HomoTyr
•D-HPh
•D-HomoPro
•beta-HomoAsn
•Azidohomoalanine
•Hse
•beta-HomoIle
•beta-HomoGlu
•beta-HomoAla
•D-Hse
•beta-HomoLeu
•beta-HomoGln
•beta-HomoPhe
■特殊氨基酸
•beta-Asp
•3-Thi
•D-Chg
•Cys (pMeBzl)
•D-beta-Asp
•Aib
•Ac6c
•Cys (pMeOBzl)
•gamma-Glu
•Abu
•Dab
•Oic
•D- gamma-Glu
•D-Abu
•Dap
•Tic
•Cys (Cam)
•Hyp
•Pra
•D-Tic
•D-Cys (Cam)
•Phg
•D-Pra
•Cys (Bzl)
•Cys (Acm)
•D-Phg
•Allo-Thr
•Epsilon-Lys
•Cys (tBu)
•Nva
•D-Allo-Thr
•D-Epsilon-Lys
•Cys (StBu)
•D-Nva
•Gly (allyl)
•5-ASA
•Met (O)
•Nle
•D-Gly (allyl)
•Bpa
•D-Met (O)
•D-Nle
•Cys (Pyrene-maleimide)
•Pip
•Cys (SNO)
•Cit
•D-1-Nal
•Nip
•Met (O)2
•D-Cit
•L-1-Nal
•2-Aze
•D-Met (O)2
•Orn
•D-2-Nal
•3-Aze
•Lys (Ac)
•D-Orn
•L-2-Nal
•[Psi (CH2NH)]
•Ac-Lys
•Pen
•D-2-Pal
•[CS-NH]
•Lys (Dde)
•D-Pen
•L-2-Pal
•Se-Met
•Tle
•Cpg
•D-3-Pal
•Se-Cys
•Ser (Octanoic acid)
•Cha
•L-3-pal
•DOPA
•Ser (Lipoic acid)
•D-Cha
•D-4-Pal
•isoGln
•D-Ser (Octanoic acid)
•Chg
•L-4-Pal
•D-isoGln
•Arg (Boc2)
•Asp-OMe
•D-Glu (OtBu)
•Lys (Z)
•Arg (NO2)
•Asp-OtBu
•Gln (Trt)
•Ser (Bzl)
•Arg (Z2)
•Asn (Trt)
•His (Boc)
•Ser (Trt)
•Arg (pbf)
•Cys (MMt)
•His (Trt)
•Ser (tBu)
•D-Arg (pdf)
•Cys (Trt)
•Tyr (propargyl)
•Tyr (tBu)
•Asp (Oall)
•D-Cys (Trt)
•Lys (Boc)
•Asp (OBn)
•Glu (Oall)
•Lys (DMT)
•D-Tyr (tBu)
•Asp (OBzl)
•Glu (OBzl)
•Lys (Fomc)
•Thr (tBu)
•Asp (OMe)
•Glu (OMe)
•Lys (Mtt)
•Trp (Boc)
•Asp (OtBu)
•Glu (OtBu)
•Lys (Trt)
•Trp (Farnesyl)
