There are a number of treatments available to treat epilepsy in general:
有许多治疗方法可用于治疗癫痫:
Anti-epileptic drugs (AEDs): many broad and narrow spectrum anticonvulsants are available. In a significant portion of the SYNGAP1 population, one or several in combination are effective in reducing seizures. However, some SYNGAP1 patients have a drug-resistant form of epilepsy and do not benefit from AEDs.
抗癫痫药物 (AED):有许多广谱和窄谱抗惊厥药可供使用。在 SYNGAP1 群体的很大一部分中,一种或几种联合使用可有效减少癫痫发作。然而,一些 SYNGAP1 患者患有耐药性癫痫,无法从 AED 中受益。
Cannabinoids: Although not tested in SYNGAP1 specifically, CBD has been shown to have antiepileptic efficacy in trials of other epilepsies. A number of SYNGAP1 patients use cannabinoids as an add-on therapy for seizure reduction.
大麻素:虽然没有专门在 SYNGAP1 中进行测试,但CBD在其他癫痫试验中已被证明具有抗癫痫功效。许多 SYNGAP1 患者使用大麻素作为减少癫痫发作的附加疗法。
Special Diets: the ketogenic diet is now accepted as an approach for reducing seizures.
特殊饮食:生酮饮食现在被认为是减少癫痫发作的一种方法。
Surgery: surgical procedures such as Vagus Nerve Stimulation (VNS) or Corpus Callosotomy may benefit carefully selected epilepsy patients with AED-resistant seizures.
手术:诸如迷走神经刺激 (VNS)或胼胝体切开术等手术可能有益于精心挑选的抗 AED 癫痫发作的癫痫患者。