Oglufanide

"目录号: HY-13718

Protein Tyrosine Kinase/RTK-

Oglufanide能够抑制VEGF，也能够抑制血管生成。

VEGFR

相关产品

Sorafenib-BIBF 1120-SU5416-Regorafenib-Ponatinib-Sunitinib-Cabozantinib-Vandetanib-Lenvatinib-Apatinib-Pazopanib-SU 5402-Foretinib-Axitinib-E-3810-

生物活性

Description

Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis.This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections.

Clinical Trial

NCT00003773

University of Southern California-National Cancer Institute (NCI)

Ovarian Cancer

February 1999

Phase 1

NCT00006037

University of Southern California-National Cancer Institute (NCI)

Colorectal Cancer

November 1999

Phase 2

NCT00017303

Cytran-National Cancer Institute (NCI)

Ovarian Cancer-Primary Peritoneal Cavity Cancer

January 2001

Phase 2

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References

[1].National Center for Biotechnology Information.