style

body{
  background: #ccc;
}
.music-pic{
    display: inline-block;
    width: 2rem /* 40/20 */;
    height: 2rem /* 40/20 */;
    overflow: hidden;
    background: url('music_icon.png') no-repeat;
    background-size: 100%;
    -webkit-animation: reverseRotataZ 1.2s linear infinite;
    position: absolute;
    z-index: 999;
    left: 82.53%;
    top: 2.4%;
    -webkit-tap-highlight-color: rgba(0, 0, 0, 0);  /*移动端，div点击瞬间，出现阴影问题*/ 
}
.music-pic.close{
   display: inline-block;
    width: 2rem /* 40/20 */;
    height: 2rem /* 40/20 */;
    overflow: hidden;
    background: url('swiper_tip.png') no-repeat;
    background-size: 100%;
    -webkit-animation: none;
}
@-webkit-keyframes reverseRotataZ{
    0%{-webkit-transform: rotateZ(0deg);}
    100%{-webkit-transform: rotateZ(-360deg);}
}
@-webkit-keyframes rotataZ{
    0%{-webkit-transform: rotateZ(0deg);}
    100%{-webkit-transform: rotateZ(360deg);}
}

html

<div class="music-pic">
    <audio id="audio2" src="./Valentin - A Little Story.mp3" preload="auto" loop="loop" ></audio>
</div>

js

需要引入jq以及微信的js
<script src="./jquery-1.7.2.min.js" type="text/javascript"></script>
<script src="./jweixin-1.0.0.js"></script> 
<script>

function autoPlayMusic() {
        // 自动播放音乐效果，解决浏览器或者APP自动播放问题
        function musicInBrowserHandler() {
            musicPlay(true);
            document.body.removeEventListener('touchstart', musicInBrowserHandler);
        }
        document.body.addEventListener('touchstart', musicInBrowserHandler);

        // 自动播放音乐效果，解决微信自动播放问题
        function musicInWeixinHandler() {
            musicPlay(true);
            document.addEventListener("WeixinJSBridgeReady", function () {
                musicPlay(true);
            }, false);
            document.removeEventListener('DOMContentLoaded', musicInWeixinHandler);
        }
        document.addEventListener('DOMContentLoaded', musicInWeixinHandler);
    }
  function musicPlay(isPlay) {
        var audio = document.getElementById('audio2');
        if (isPlay && audio.paused) {
            audio.play();
        }
        if (!isPlay && !audio.paused) {
            audio.pause();
        }
    };
  autoPlayMusic();

// 关闭音乐
$('.music-pic').click(function () {
    if($('.music-pic').hasClass('close')){
        document.getElementById("audio2").muted=false;
        $('.music-pic').removeClass('close');
    }else {
        $('.music-pic').addClass('close');
        document.getElementById("audio2").muted=true;
    }
});