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Mutant IDH1 inhibitor ???????????????????????????IDH1 R132H???????????????IC50????????? 72 nM???
Isocitrate Dehydrogenase (IDH)
相关产品
Enasidenib-AGI-5198-Ivosidenib-AGI-6780-Mutant IDH1-IN-1-Mutant IDH1-IN-2-GSK864-
生物活性
Description
Mutant IDH1 inhibitor is a potent mutantIDH1 R132Hinhibitor withIC50of < 72 nM.
IC50& Target
IC50: < 72 nM (mutant IDH1 R132H)
In Vitro
Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1].
References
