G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes. These cell surface receptors act like an inbox for messages in the form of light energy, peptides, lipids, sugars, and proteins. Such messages inform cells about the presence or absence of life-sustaining light or nutrients in their environment, or they convey information sent by other cells. GPCRs bind a tremendous variety of signaling molecules, yet they share a common architecture that has been conserved over the course of evolution. Many present-day eukaryotes — including animals, plants, fungi, and protozoa — rely on these receptors to receive information from their environment. For example, simple eukaryotes such as yeast have GPCRs that sense glucose and mating factors. Not surprisingly, GPCRs are involved in considerably more functions in multicellular organisms. Humans alone have nearly 1,000 different GPCRs, and each one is highly specific to a particular signal.
Histamine Receptor: https://www.tsbiochem.com/target/Histamine-Receptor
Adrenergic Receptor: https://www.tsbiochem.com/target/Adrenergic-Receptor
5-HT Receptor: https://www.tsbiochem.com/target/5-HT-Receptor
Dopamine Receptor: https://www.tsbiochem.com/target/Dopamine-Receptor
OX Receptor: https://www.tsbiochem.com/target/OX-Receptor
Hedgehog/Smoothened: https://www.tsbiochem.com/target/Hedgehog-Smoothened
Adenosine Receptor: https://www.tsbiochem.com/target/Adenosine-Receptor
Annexin A: https://www.tsbiochem.com/target/Annexin-A
Bombesin Receptor: https://www.tsbiochem.com/target/Bombesin-Receptor
cAMP: https://www.tsbiochem.com/target/cAMP
Cannabinoid Receptor: https://www.tsbiochem.com/target/Cannabinoid-Receptor
CaSR: https://www.tsbiochem.com/target/CaSR
cholecystokinin: https://www.tsbiochem.com/target/cholecystokinin
Endothelin Receptor: https://www.tsbiochem.com/target/Endothelin-Receptor
Glucagon Receptor: https://www.tsbiochem.com/target/Glucagon-Receptor
GNRH Receptor: https://www.tsbiochem.com/target/GNRH-Receptor
GPCR19: https://www.tsbiochem.com/target/GPCR19
GRK: https://www.tsbiochem.com/target/GRK
GTPase: https://www.tsbiochem.com/target/GTPase
LPA Receptor: https://www.tsbiochem.com/target/LPA-Receptor
Melatonin Receptor: https://www.tsbiochem.com/target/Melatonin-Receptor
PAFR: https://www.tsbiochem.com/target/PAFR
Prostaglandin Receptor: https://www.tsbiochem.com/target/Prostaglandin-Receptor
Protease-activated Receptor: https://www.tsbiochem.com/target/Protease-activated-Receptor
S1P Receptor: https://www.tsbiochem.com/target/S1P-Receptor
SGLT: https://www.tsbiochem.com/target/SGLT
Sigma receptor: https://www.tsbiochem.com/target/Sigma-receptor
Somatostatin: https://www.tsbiochem.com/target/Somatostatin
Vasopressin Receptor: https://www.tsbiochem.com/target/Vasopressin-Receptor
CXCR: https://www.tsbiochem.com/target/CXCR
Opioid Receptor: https://www.tsbiochem.com/target/Opioid-Receptor
Melanocortin Receptor: https://www.tsbiochem.com/target/Melanocortin%20Receptor
Neuropeptide Y Receptor: https://www.tsbiochem.com/target/Neuropeptide%20Y%20Receptor
Leukotriene Receptor: https://www.tsbiochem.com/target/Leukotriene%20Receptor
EBI2/GPR183: https://www.tsbiochem.com/target/EBI2-GPR183
GPR: https://www.tsbiochem.com/target/GPR
Ras: https://www.tsbiochem.com/target/Ras
GHSR: https://www.tsbiochem.com/target/GHSR
TSH Receptor: https://www.tsbiochem.com/target/TSH%20Receptor
Oxytocin Receptor: https://www.tsbiochem.com/target/Oxytocin%20Receptor3
Guanylate cyclase: https://www.tsbiochem.com/target/Guanylate%20cyclase
CRFR: https://www.tsbiochem.com/target/CRFR
Apelin receptor: https://www.tsbiochem.com/target/Apelin%20receptor
Neurokinin receptor: https://www.tsbiochem.com/target/Neurokinin%20receptor
Adiponectin receptor: https://www.tsbiochem.com/target/Adiponectin-receptor