The canonical method to estimate the causal effect of a continuous exposure on a continuous outcome using an instrumental variable (IV) for one-sample MR.
在单样本孟德尔随机化（MR）中，使用工具变量（IV）来估计连续暴露对连续结局的因果效应的标准方法。
For this method to provide a valid causal estimate of the exposure on the outcome, genetic variants must satisfy the MR assumptions and the model describing the association between the genetic variant and outcome must be correctly specified.
要使这种方法对暴露因素对结局的影响提供有效的因果估计，遗传变异必须满足孟德尔随机化（MR）假设，且描述遗传变异与结局之间关联的模型必须正确设定。
