PMID: 33176148

这篇文章数据分析步骤写得比较有条理
分析增强子需要的数据：
We profiled several post-translational histone modifications by chromatin immunoprecipitation sequencing (ChIP-seq), including H3K4me1, H3K4me3, H3K27me3, H3K27ac, and H3K18ac, following ARID1A-depletion in 12Z human endometrial epithelial cells (Zeitvogel et al., 2001). These data were used in conjunction with assay for transposase-accessible chromatin sequencing (ATAC-seq) and total RNA-seq datasets from ARID1A-depleted 12Z cells (Wilson et al., 2019), which allowed us to build a comprehensive model of chromatin state transitions accompanying ARID1A loss (Figures 1A and and1B).1B).
最重要是要有：histone H3K27ac

SEdb: a comprehensive human super-enhancer database

SEdb, http://www.licpathway.net/sedb).
Edb provides: (i) comprehensive genetic and epigenetic annotation of super-enhancers including common SNPs, motif changes, eQTLs, risk SNPs, TFBSs, CRISPR/Cas9 target sites, DHSs and enhancers, and user-friendly displays with interactive tables; (ii) online analysis tools such as ‘Gene-SE analysis’, ‘SNP-SE analysis’, ‘Overlap analysis’ and analysis tools from external links such as GREAT and Galaxy for search results; (iii) a customized genome browser for user-friendly visualizing of genomic context information of super-enhancers and links for visualizing data in the UCSC genome browser by adding custom tracks; (iv) user-friendly browsing of samples; (v) a CGI interface that can be easily used and quickly generate super-enhancers that overlap with the user-submitted genome location; (vi) detailed internal information on super-enhancer elements, including related annotations and related analysis tools; (vii) overlapping contacts with other super-enhancers in different samples.

SEA version 3.0: a comprehensive extension and update of the Super-Enhancer archive

the super-enhancer archive version 3.0 (SEA v. 3.0, http://sea.edbc.org)