多肽定制服务

多肽介绍

多肽是氨基酸以肽键连接在一起形成的化合物，具有多种生物学功能，例如抗血栓形成、抗高血压、抗菌、抗病毒、抗癌、抗氧化、免疫调节、降胆固醇等，目前已广泛用于功能分析、抗体研究、疫苗开发及药物研发等领域。

MCE 配备强大的技术人才团队和国际先进的设备，提供全方位的高质量定制肽服务，包括快速肽合成、标准化学肽合成、肽修饰、肽库和重组多肽表达，以满足生物与药物发现研究中不断增长的多肽需求。

■可选规格： 毫克（mg）级至公斤（kg）级。

■纯度范围： 粗肽、脱盐、70% 至 98%。

■广泛修饰： 可提供酰胺化、乙酰化、甲基化、磷酸化、标记及偶联等 300+ 种不同 修饰。

■合成技术： 结合固相合成及液相合成，微波和连接技术。

■免费咨询： 专业的 MCE 技术团队为您解答多肽定制的售前与售后的技术问题。

多肽修饰

■N 端修饰

•Ac

•Allyl

•Cholesteryl-

•N-Propargylglycine-

•Fmoc

•Acryl

•Fructose-

•Ad

•CBZ

•Alloc

•Glucose-

•BPS-

•Boc

•Pyr

•Morpholine-4-carbonyl-

•Bz

•D-Pyr

•NTriAc

•Trans-Cinnamoyl

•Bz (5-NH2,2-NO2)

•LA-

•PhAc

•2-Furoyl

•Bz (4-F)

•Mpa-

•Py-Ac

•Methacryl-

•Bz (4-NO2)

•Tos

•N-Amidinoglycine

•BPA-

■C 端修饰

•-pNA

•-OMe

•-ONP

•-OSu

•-NH2

•-OEt

•-AMC

•-NHMe

•-ol

•-OBzl

•-AFC

•-NHEt

■脂肪酸化

•For

•MeOSuc

•5-Hexynoic acid

•F-Lau-

•MeOCO

•Iba

•Heptanedioic acid

•Myr-

•2-Br-Ac

•pentenoic acid

•Oct-

•F-Myr-

•2-Cl-Ac

•pentinoyl

•F-Oct-

•Pentadeconyl-

•2-I-Ac

•Hex-

•Dec-

•Pal-

•OH-Ac

•5-heptenoic acid

•Sebacic acid

•Cys (Pal)

•3-Bromopropionyl

•Trans-3-hexenoyl-

•F-Dec-

•Pam3C-

•But-

•Linoletic-

•Undecyl-

•Ste-

•Suc

•10,12-Pentacosadiynoic acid

•Lau-

•Octanedioic acid

■甲基化

•Lys (Me)

•Arg (Me)

•Tyr (Me)

•Tyr (Et)

•Lys (Me2)

•Arg (Me2)asymmetrical

•Thr (Me)

•D-Tyr (Et)

•Lys (Me3)

•Arg (Me2) symmetrical

•Ser (Me)

■磷酸化

•pSer

•D-pSer

•Di-sites in sequence

•4-sites in sequence

•pTyr

•D-pTyr

•Tri-sites in sequence

•5-sites in sequence

•pThr

•D-pThr

■支肽

•Symmetric 2 Branches

•Symmetric 4 Branches

•Symmetric 8 Branches

•Lys symmetric 2 Branches

•Lys symmetric 4 Branches

•Lys symmetric 8 Branches

•Orn symmetric 2 Branches

•Orn symmetric 4 Branches

•Orn symmetric 8 Branches

•Glu 2 Branches (Pure)

•Glycerol 3 Branches ester

•Thr (Peptide2)

•Ser (Peptide2)

•Lys (Peptide2)

■环肽

•Mono Disulfide bridge

•Double Disulfide bridge

•Triple Disulfide bridge

•Random Triple Disulfide bridge

•Same Sequence Inter-Disulfide bridge by Cys oxidation

•Different Sequence Inter-Disulfide bridge by Cys oxidation

•Oxidation between Se-Cys

•Amide Cyclic (end)

•Amide Cyclic (side chain) by Lys

•Amide Cyclic (side chain) by Orn

■荧光/染料标记

•Biotin-

•FITC-

•Dansyl-

•Lys (Dnp)

•DeThioBiotin

•-ED-FITC

•-EDDansyl

•D-Lys (Dnp)

•-EDBiotin

•-Lys (FITC)-

•-Lys (Dansyl)-

•Dab (Dnp)

•Glu (Biotin-PEG2)

•-Lys (FITC)

•-Lys (Dansyl)

•Dap (Dnp)

•-Lys (Biotin)-

•Lys (Ahx-FITC)

•Dansli-e-Lys

•-EDDnp

•-Lys (Biotin)

•FITC-e-Lys

•Dansyl-Ahx-

•-Lys (LC-Biotin)-

•FITC-Ahx-

•5-FAM-

•-Lys (LC-Biotin)

•5-TAMRA-

•5,6-FAM

•Biotin-e-Lys

•5 (6)-TAMTA-

•6’FAM

•Lys (S-S-Biotin)

•-EDYAMRA

•-ED-5-FAM

•Biotin-Ahx-

•-Lys (TAMRA)-

•-Lys (5-FAM)-

•Orn (Bio)

•-Lys (5-TAMRA)

•Lys (5,6-FAM)

•MCA-

•5-TAMRA-e-Lys

•-Lys (5-FAM)

•-Lys (MCA)-

•5-TAMRA-Acp

•5-FAM-E-Lys

•-Lys (MCA)

•5-FAM-Ahx-

•Lys (MCA)-

■BSA、KLH、OVA 偶联

•BSA-Peptide N terminus

•KLH-Peptide N terminus

•OVA-Peptide N terminus

•BSA-Peptide C terminus

•KLH-Peptide C terminus

•OVA-Peptide C terminus

•BSA-Peptide via Cys

•KLH-Peptide via Cys

•OVA-Peptide via Cys

■Phe & Tyr 衍生物

•D-2-Cl-Phe

•D-4-F-Phe

•L-2-Me-Phe

•L-3-I-Tyr

•L-2-Cl-Phe

•L-4-F-Phe

•D-4-Me-Phe

•D-3,5-DiI-Tyr

•D-3-Cl-Phe

•D-4-NO2-Phe

•L-4-Me-Phe

•L-3,5-DiI-Tyr

•L-3-Cl-Phe

•L-4-NO2-Phe

•D-4-NH2-Phe

•D-3-NO2-Tyr

•D-4-Cl-Phe

•D-4-I-Phe

•L-4-NH2-Phe

•L-3-NO2-Tyr

•L-4-Cl-Phe

•L-4-I-Phe

•D-3-Cl-Tyr

•D-3,5-DiNO2-Tyr

•D-3,4-DiCl-Phe

•D-3-CN-Phe

•L-3-Cl-Tyr

•L-3,5-DiNO2-Tyr

•L-3,4-DiCl-Phe

•L-3-CN-Phe

•D-3,5-DiCl-Tyr

•L-3-F-Tyr

•D-4-Br-Phe

•D-4-CN-Phe

•L-3,5-DiCl-Tyr

•L-4-NO2-Phg

•L-4-Br-Phe

•L-4-CN-Phe

•D-3,5-DiBr-Tyr

•D-4-NO2-Phg

•D-3-F-Phe

•D-2-Me-Phe

•L-3,5-DiBr-Tyr

•L-3,5-DiF-Phe

•L-3-F-Phe

•D-3-I-Tyr

■Linker

•Gly

•Ava

•AEA

•GABA

•Beta-Ala

•Ahx

•Ado

•Mini-PEG

•Mini-PEG2

•Mini-PEG3

•PEG4

■树脂

•peptide on Wang Resin

•peptide on 2-CTC Resin

•peptide on Rink Amide AM Resin

•peptide on Rink Amide MBHA Resin

■D 型氨基酸

•D-Ala

•D-Lys

•D-Glu

•D-Tyr

•D-Arg

•D-Met

•D-Gln

•D-Thr

•D-Asp

•D-Pro

•D-His

•D-Trp

•D-Asn

•D-Phe

•D-Leu

•D-Val

•D-Cys

•D-Ser

■同型氨基酸

•Har

•HomoCit

•beta-HomoMet

•beta-HomoSer

•D-Har

•D-HomoCit

•beta-HomoPro

•beta-HomoThr

•Hcy

•HomoLeu

•beta-HomoVal

•beta-HomoTrp

•HPh

•HomoPro

•beta-HomoAsp

•beta-HomoTyr

•D-HPh

•D-HomoPro

•beta-HomoAsn

•Azidohomoalanine

•Hse

•beta-HomoIle

•beta-HomoGlu

•beta-HomoAla

•D-Hse

•beta-HomoLeu

•beta-HomoGln

•beta-HomoPhe

■特殊氨基酸

•beta-Asp

•3-Thi

•D-Chg

•Cys (pMeBzl)

•D-beta-Asp

•Aib

•Ac6c

•Cys (pMeOBzl)

•gamma-Glu

•Abu

•Dab

•Oic

•D- gamma-Glu

•D-Abu

•Dap

•Tic

•Cys (Cam)

•Hyp

•Pra

•D-Tic

•D-Cys (Cam)

•Phg

•D-Pra

•Cys (Bzl)

•Cys (Acm)

•D-Phg

•Allo-Thr

•Epsilon-Lys

•Cys (tBu)

•Nva

•D-Allo-Thr

•D-Epsilon-Lys

•Cys (StBu)

•D-Nva

•Gly (allyl)

•5-ASA

•Met (O)

•Nle

•D-Gly (allyl)

•Bpa

•D-Met (O)

•D-Nle

•Cys (Pyrene-maleimide)

•Pip

•Cys (SNO)

•Cit

•D-1-Nal

•Nip

•Met (O)2

•D-Cit

•L-1-Nal

•2-Aze

•D-Met (O)2

•Orn

•D-2-Nal

•3-Aze

•Lys (Ac)

•D-Orn

•L-2-Nal

•[Psi (CH2NH)]

•Ac-Lys

•Pen

•D-2-Pal

•[CS-NH]

•Lys (Dde)

•D-Pen

•L-2-Pal

•Se-Met

•Tle

•Cpg

•D-3-Pal

•Se-Cys

•Ser (Octanoic acid)

•Cha

•L-3-pal

•DOPA

•Ser (Lipoic acid)

•D-Cha

•D-4-Pal

•isoGln

•D-Ser (Octanoic acid)

•Chg

•L-4-Pal

•D-isoGln

•Arg (Boc2)

•Asp-OMe

•D-Glu (OtBu)

•Lys (Z)

•Arg (NO2)

•Asp-OtBu

•Gln (Trt)

•Ser (Bzl)

•Arg (Z2)

•Asn (Trt)

•His (Boc)

•Ser (Trt)

•Arg (pbf)

•Cys (MMt)

•His (Trt)

•Ser (tBu)

•D-Arg (pdf)

•Cys (Trt)

•Tyr (propargyl)

•Tyr (tBu)

•Asp (Oall)

•D-Cys (Trt)

•Lys (Boc)

•Asp (OBn)

•Glu (Oall)

•Lys (DMT)

•D-Tyr (tBu)

•Asp (OBzl)

•Glu (OBzl)

•Lys (Fomc)

•Thr (tBu)

•Asp (OMe)

•Glu (OMe)

•Lys (Mtt)

•Trp (Boc)

•Asp (OtBu)

•Glu (OtBu)

•Lys (Trt)

•Trp (Farnesyl)